Résultats du segment 2 de l'événement Cook Out Southern 500 2021
06 septembre
Caroline du Sud - Darlington
Darlington Raceway 2,20 km (1,37 mi)
| P | # | Pilote | Propriétaire | Moteur | Tours | Points | PP |
| 1 | 5 | Kyle Larson | Hendrick Motorsports | Chevrolet | 230 | 10 | 1 |
| 2 | 20 | Christopher David Bell | Joe Gibbs Racing | Toyota | 230 | 9 | |
| 3 | 42 | Ross L. Chastain | Chip Ganassi Racing | Chevrolet | 230 | 8 | |
| 4 | 11 | Denny Hamlin | Joe Gibbs Racing | Toyota | 230 | 7 | |
| 5 | 4 | Kevin Harvick | Stewart-Haas Racing | Ford | 230 | 6 | |
| 6 | 1 | Kurt Busch | Chip Ganassi Racing | Chevrolet | 230 | 5 | |
| 7 | 22 | Joey Logano | Team Penske | Ford | 230 | 4 | |
| 8 | 9 | Chase Elliott | Hendrick Motorsports | Chevrolet | 230 | 3 | |
| 9 | 12 | Ryan Blaney | Team Penske | Ford | 230 | 2 | |
| 10 | 7 | Corey Daniel LaJoie | Spire Motorsports | Chevrolet | 230 | 1 |