Résultats du segment 1 de l'événement Cook Out Southern 500 2022
05 septembre
Caroline du Sud - Darlington
Darlington Raceway 2,20 km (1,37 mi)
| P | # | Pilote | Propriétaire | Moteur | Tours | Points | PP |
| 1 | 24 | William Byron | Hendrick Motorsports | Chevrolet | 115 | 10 | 1 |
| 2 | 11 | Denny Hamlin | Joe Gibbs Racing | Toyota | 115 | 9 | |
| 3 | 18 | Kyle Busch | Joe Gibbs Racing | Toyota | 115 | 8 | |
| 4 | 20 | Christopher David Bell | Joe Gibbs Racing | Toyota | 115 | 7 | |
| 5 | 19 | Martin Truex Jr. | Joe Gibbs Racing | Toyota | 115 | 6 | |
| 6 | 1 | Ross L. Chastain | Trackhouse Racing Team | Chevrolet | 115 | 5 | |
| 7 | 8 | Tyler Reddick | Richard Childress Racing | Chevrolet | 115 | 4 | |
| 8 | 43 | Erik Jones | Petty GMS Motorsports | Chevrolet | 115 | 3 | |
| 9 | 12 | Ryan Blaney | Team Penske | Ford | 115 | 2 | |
| 10 | 45 | Darrell Wallace Jr. | 23XI Racing | Toyota | 115 | 1 |