Résultats du segment 1 de l'événement O’Reilly Auto Parts 253 2021
21 février
Floride - Daytona Beach
Daytona International Speedway Road Course 5,81 km (3,61 mi)
| P | # | Pilote | Propriétaire | Moteur | Tours | Points | PP |
| 1 | 9 | Chase Elliott | Hendrick Motorsports | Chevrolet | 16 | 10 | 1 |
| 2 | 22 | Joey Logano | Team Penske | Ford | 16 | 9 | |
| 3 | 11 | Denny Hamlin | Joe Gibbs Racing | Toyota | 16 | 8 | |
| 4 | 2 | Brad Keselowski | Team Penske | Ford | 16 | 7 | |
| 5 | 1 | Kurt Busch | Chip Ganassi Racing | Chevrolet | 16 | 6 | |
| 6 | 5 | Kyle Larson | Hendrick Motorsports | Chevrolet | 16 | 5 | |
| 7 | 19 | Martin Truex Jr. | Joe Gibbs Racing | Toyota | 16 | 4 | |
| 8 | 3 | Austin Dillon | Richard Childress Racing | Chevrolet | 16 | 3 | |
| 9 | 4 | Kevin Harvick | Stewart-Haas Racing | Ford | 16 | 2 | |
| 10 | 17 | Christopher Buescher | Roush Fenway Racing | Ford | 16 | 1 |